Trophectoderm biopsy (TOBI) and preimplantation testing (PGT)

Tobi

In specific clinical situations clearly defined by the Reproductive Medicine Act (FMedG), it is allowed and possible to genetically analyze a small number of embryonic cells.

Medical indications for PGT treatment include:

  • Three or more IVF/ICSI procedures where implantation has failed
  • Three or more miscarriages (spontaneous miscarriages) documented by ultrasound
  • A known chromosomal abnormality and/or a known gene mutation in at least one parent that may lead to a genetic disease in the child (Note: only strictly defined mutations can be legally tested; the list of these diseases is constantly updated)

In order to undergo preimplantation genetic testing (PGT), the couple must go through a complete IVF/ICSI cycle.

The cost of a PGT is nevercovered by the IVF fund .

Instead of embryo transfer of a blastocyst, our biologists perform a biopsy of the blastocyst, which is frozen after the procedure.

The part of the embryo that will later become the fetus is never biopsied. Only a few trophectoderm cells are extracted, which are specially prepared and then sent to a specialized genetic laboratory for further analysis. Normally, the analysis is completed within a week.

If at least one embryo is found without chromosomal abnormality and/or targeted gene mutation (which was the reason for the PGT), the next step is a simple embryo transfer of the selected, unaffected embryo.

Kinderwunschklinik-Graz-Kinderwunsch-baby

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